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Prednisone is a synthetic cortisone.
Prednisone has no substantial biological effects until converted via hepatic metabolism to prednisolone.
We emphasize, however, that for some forms of vasculitis that do not respond to steroids prednisone alone, cyclophosphamide may be a life saving medicine.
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In a case series published by shaffer and phillips, 55 the association of oral cyclophosphamide and prednisone was successful in achieving a complete remission cr in all of the 9 consecutive acquired hemophilia patients...
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